Next Gen Sequencing - An introduction

I was asked to provide some information on the different platforms available for NGS as well as the basic technical differences between the various platforms. Given that there are already a number of good resources available out there, I will list them below as an initial introductory list to next generation sequencing.

Roche – 454

Life Tech – SOLiD and Ion Torrent

Illumina – HiSeq and MiSeq

PacBio - SMRT

Complete Genomics – DNA NanoBall

AZCO Biotech – MaxSeq

Elaine Mardis at NHGRI Youtube video: http://www.youtube.com/watch?v=PMIF6zUeKko along with http://www.genome.gov/12514288 other lectures on genome sequencing.

BlueSeq YouTube Video: http://www.youtube.com/watch?v=NpQxMiRk9hE

Comparing current platforms as well as future/emerging platforms (i.e. nanopore technology).

https://sites.google.com/a/brown.edu/bioinformatics-in-biomed/online-review-articles  A good list of review articles on Next Gen Sequencing

http://www.stanford.edu/group/barronlab/PubPdfs/2011/Landscape%20of%20Next%20Generation%20Sequencing%20Technologies.pdf A publication that discusses all the chemistries of Next Gen.